absorption iz stomach (25%)
metabolized to acetaldehyde by stomach and LI
rate limiting enzyme: gastric alcohol dehydrogenase
men have more of it than women, per pound body wt
metabolism of ethanol-->acetaldehyde-->acetate
one NAD+-->NADH with each of above oxidation rxns
drinking binge w/o food intake-->high NADH relative to NAD
and of course you remember that NADH is made from niacin, vitamin B3
alcohol abuse is the most common cause of thiamine deficiency, B1
( biochemistry, nutrition and pathology notes, merged with black book feb 2013 )