INTERESTING TIMES

What causes a granular surface on the kidneys?
benign nephrosclerosis-->patchy ischemic atrophy-->focal loss of parenchyma-->granular surface
common in diabetics, also dt HTN
( from Miller's notes )

The "rare syndromes" that are associated with multiple lipomas, according to my minor surgery notes, are "Gardner's syndrome and two benign conditions--multiple symmetrical lipomatosis and Dercum's disease. In the latter, the lipomas are painful". I had to look it up because my sister's husband is covered in them, and because in the last 2 years I've begun to develop them all over my body including strange locations such as over the biceps femoris tendon in my posteriolateral popliteal area--very small so far--I suspect a hormonal etiology. More occur in women after menopause, and familial types onset at adolescence. With some types there is an increased incidence of breast, endometrial and thyroid cancer. Sounds like it may be related with estrogen dominance. This would be supported by the increased incidence with obesity. There is also an association with multiple endocrine neoplasia type I (lipomas and pancreatic, parathyroid, pitutitary tumors). The list of hormonal associations increases the deeper I dig. There are also fat deposits associated with spina bifida. Looks like nobody has studied hormones in lipomatosis patients, but based on my short survey I have just now formed the opinion that is expressed in the title of this entry.
( notes: fyi, when something is marked with triple questionmarks it means that the source is not convincing and I kinda doubt it, but I'm recording it for future reference anyway )

CANCERS PROVOKED BY EXPOSURE
acute leukemia most common
papillary carcinoma of the thyroid
osteogenic sarcoma
( more )