liveonearth: (Default)
 
 
 

“The state of flow, like the path that bears its name, is volatile, unpredictable, and all-consuming.  Flow feels like the meaning of life for good reason.  The neurochemicals that underpin the state are among the most addictive drugs on earth.  Equally powerful is the psychological draw.  scientists who study human motivation have lately learned that after basic survival needs have been met, the combination of autonomy (the desire to direct your own life), mastery (the desire to learn, explore, and be creative), and purpose (the desire to matter, to contribute to the world) are our most powerful intrinsic drivers—the three things that motivate us most.  All three are deeply woven through the fabric of flow.  Thus toying with flow involves tinkering with primal biology: addictive neurochemistry, potent psychology, and hardwired evolutionary behaviors.  Seriously, what could go wrong?”
 

—Steven Kotler in The Rise of Superman; Decoding the Science of Ultimate Human Performance, p158, in Ch10 entitled The Dark Side of Flow.

liveonearth: (Default)
 
 
 
On Monday October 14 I attended what was advertised as a movie about homeopathy.  It was listed in the email that goes out to all staff, faculty and students at NUNM, the National University of Natural Medicine.  I was one of two staff present, the other one being there because she was required to for her job.

I attended this event because I am writing a book about homeopathy, or rather about the culture and psychology that surrounds it.  I am not a believer.  The people who at the event made the assumption that I was, and I made no effort to dissuade them.  I presume that NUNM hosts these events because Boiron donates money, but I could be wrong.

The man who greeted me at the event was the same man I had called to RSVP.  He was nice enough but he had terrible breath and I had to steel myself not to take several steps back whenever he spoke.  He also had a huge pot belly.  When I walked in the door he was telling his own conversion story, about how 30 years ago he'd been sick and had exhausted all the options given by conventional medicine.  Then he'd tried homeopathy and gotten better, and he had never looked back.  It is this kind of uncritical conversion story that gets repeated ad nauseum by homeopathy believers.  I believe they need to repeat it, to hear themselves repeating it, to maintain their belief.  His breath turned my stomach and his story gave me no reason to respect his critical thinking prowess, so I escaped as quickly as possible, but not before I learned that he is a rep for Boiron, one of apparently just two for the entire west coast.  The other rep was also present and made no better representation of the health that can be attained by way of homeopathy.  She engaged me in conversation for a little while, marketing her ND practice in PDX and eating M&M's one by one.  If this is the best Boiron can do for reps they are definitely going down.

They were giving away free pizza and the host had asked me on the telephone what my favorite kind of pizza was.  I answered jalapeno and anchovy, but when I got there my favorite was not.  Apparently the restaurant did not have anchovies and only jar jalapenos though fresh are easily available.  All but one of the huge stack of pizzas were gluten free, however.  I suppose they think that all naturopaths avoid gluten.

The talk that came before the movie was supposed to be a summary of the regulatory status of homeopathy in the US, but really it was an advertisement for Boiron.  The focus was on Boiron's efforts to influence the FDA's position, on a great personal connection that Boiron has in the FDA, and on how the FDA regs don't really stop the sale of homeopathy.  I was somewhat irritable because being in the supplement business I know a little bit about how the FDA has impacted OUR sales of homeopathics, and the Boiron rep was clearly ignorant of that situation.  We've discontinued all sales of LM's (compounded liquid homeopathics),  remedies made from DEA-regulated drugs (opium, etc), and nosodes (remedies made from diseased material, like medorrhinum).  These changes have been in response to shifts in the FDA's stance. 

There was also angry mention of the Australian analysis of everything known about homeopathy which resulted in them dropping it from their publicly funded healthcare program.  They decided it was not effective for treating any conditionFrance and other countries have dropped homeopathy from public funding due to lack of evidence, but the speaker at this event insisted that the Australian assessment was biased and wrong and would be reversed.  Yeah, right.

I learned little from this presentation but I did eat some pizza.  It was OK.

More interesting than the update about regulation was the bit that they said about the "grant" that Boiron had provided to the CEDH (Center for Education and Development of Clinical Homeopathy) to start a "Clinical Homeopathy" program, with the subtitle "Integrate Homeopathy Into Your Daily Practice".  It isn't really a grant, it is an expenditure on a marketing effort intended to brainwash more people into believing.  The CEDH exists to separate the name Boiron from the "educational" program. 

In the first "module" of the 4-part educational program they have 22 students enrolled, most of whom are NUNM students.  This makes sense as a lot of people enter naturopathic school already sure about homeopathy and intending to use it.  It also makes sense because shifts in the ND curriculum have removed all five of the homeopathy classes that I was required to take, and instruction in homeopathy is supposed to be blended in with the subject matter in "blocks" that address organ systems one at a time.  According to the students the majority of professors are not teaching much, if any homeopathy, and yet homeopathy is still on the ND clinical board exams.  The students are panicked about the exams and seeking training in homeopathy outside of the NUNM ND curriculum.  Boiron and the CEDH are taking advantage of this situation to secure their future market.

After the talking they finally started the movie, a good hour after the email had said it would begin.  Entitled Magic Pills, the movie is another brainwashing effort along the lines of Just One Drop.  This one attempts to directly address all the complaints that skeptics have about homeopathy, talking about confirmation bias as a reason that scientists won't even consider homeopathy, and repeating the usual homeopathy hypnotic anchor of "it works" (kind of like "build a wall" for Trump).  They also expressed quite a bit of anger at moles such as myself who do not believe but show up to their events and practices wanting to gain information to undermine their efforts.

From my perspective Magic Pills was a weaker piece of brainwashing than Just One Drop but the believers in the scant audience were nodding along.  The use of the title was an effort to take one of the phrases used by skeptics and turn it into a hypnotic anchor for the believers.  I was keeping a tally of all the mentions of "it works", all the testimonials by lay people, medical professionals and PhD's, and all the conversion stories.  These are the standard approaches of homeopaths in getting people to believe.  In the future it might be worth tracking "magic pills" references.  Skeptics should be aware that believers may have been brainwashed to specifically resist the terms that they are using.  Repetition is one of the essential tools of hypnosis/brainwashing.  I had to leave before the end which could be have been more powerful than the anti-skeptic lead-in, but I confess I did not regret leaving.  I had to take a shower when I got home.




 
liveonearth: (Default)
 Man is
and remains
an animal.
Here a beast of prey,
there a housepet,
but always an animal.
~~Joseph Goebbels (German Nazi propagandist)
(source: https://www.goodreads.com/author/quotes/281832.Joseph_Goebbels)
liveonearth: (Default)

There are those who would say I am an a-hole because I have a hard time telling apart the three Indian men that I know.  They are all great people, and I really have nothing against their origins or accent or skin tone.  I just didn't grow up around people from India.  I knew more people of African and Asian origin, and they look less the same to me than people from India.  I was slightly reassured that I am not actually an a-hole when I read this article (below).  World wide, across many cultures, people are likely to have difficulty distinguishing individuals of a race that is entirely unfamiliar.  This is not xenophobia, and it is not a-holishness.  It is just a fact of our evolution, or rather a fact of brain development.

In our first couple years of lives our brains grow very large.  Neural connections form based on our experience.  When we do not have experience of something, part of the brain gets "pruned" away.  A lot of pruning happens when we are toddlers.  It has to happen because we are having a lot of experiences and the brain has to get rid of unused parts in order to make room for all the connections we are making based on living a rich life.  When I was toddling, I didn't know any Indian men.  When I met one or two later they were unusual and they got lumped together into a category.  Now that I'm in my 50's I'm finding it embarrassingly hard to rewire fast enough to keep up with all the new people in my world.

It occurs to me that not being able to tell people apart is a basis for fear.  It is perhaps one of the reasons that humans are naturally untrusting of those who look very different from themselves.



RACIAL PROSOPAGNOSIA 2017

https://www.scientificamerican.com/article/some-people-suffer-from-face-blindness-for-other-races/

Some People Suffer from Face Blindness for Other Races

Certain individuals are seriously impaired when it comes to recognizing individuals of another color

By Agata Blaszczak-Boxe on May 1, 2017

We tend to be worse at telling apart faces of other races than those of our own race, studies have found. Now research shows some people are completely blind to features that make other-race faces distinct. Such an impairment could have important implications for eyewitness testimony in situations involving other-race suspects.

The ability to distinguish among members of one's own race varies wildly: some people can tell strangers apart effortlessly, whereas others cannot even recognize the faces of their own family and friends (a condition known as prosopagnosia). Psychologist Lulu Wan of the Australian National University and her colleagues wanted to quantify the distribution of abilities for recognizing other-race faces. They asked 268 Caucasians born and raised in Australia to memorize a series of six Asian faces and conducted the same experiment, involving Caucasian faces, with a group of 176 Asians born and raised in Asia who moved to Australia to attend university. In 72 trials, every participant was then shown sets of three faces and had to point to the one he or she had learned in the memorization task.

The authors found that 26 Caucasian and 10 Asian participants—8 percent of the collective study population—did so badly on the test that they met the criteria for clinical-level impairment. “We know that we are poor at recognizing other-race faces,” says Jim Tanaka, a professor of psychology at the University of Victoria in British Columbia, who was not involved in the research. “This study shows just how poor some people are.” Those individuals “would be completely useless in terms of their legal value as an eyewitness,” says study co-author Elinor McKone, a professor of psychology at the Australian National University. The world's legal systems do not, however, take into account individual differences in other-race face recognition, she notes.

One's lifetime level of exposure to other races could factor into a person's ability to recognize people of another color, according to the findings published in the January issue of the Journal of Experimental Psychology: General. Among 106 Asian participants born and raised in Australia, only about 3 percent were blind to Caucasian faces. In comparison, nearly 6 percent of the Asians born and raised in Asia had the impairment.

The effect extends to other races, too. In a study published in 2001 in Psychology, Public Policy, and Law, black people recruited in South African shopping malls, who had average levels of interracial contact, were better at recognizing faces of their own race than of others.

This article was originally published with the title "Are You Blind to Faces of Other Races?"

 

 


liveonearth: (moon)
Today I finally got my updated living will / medical power of attorney updated, witnessed, and notarized, and I also officialized my first last will and testament.  My friends asked me if I was planning on leaving.  It's a good question to ask a person who is settling their affairs at my age, but no, in spite of the depressing state of affairs in the world, my life is good enough that I'm planning to stick around and see what happens next.   In my living will today I specified what I want done if I lose my mind (travel to a country where euthanasia is allowed for dementia--Switzerland or Nederlands allow it as of now), and also where I want my brain to go (for research purposes, to the Oregon Brain Bank of OHSU).  I'm excited and glad to have this done.  I've been meaning to do it and rewriting it for a decade now.

The real reason I was motivated to complete these documents at the age of 50 is that I can tell that I am losing cognitive function.  It shows up in many ways, and people routinely fight me on this observation, saying that I'm fine, it's normal aging, blah blah blah.  Let me just say that I used to be very smart, and I'm not any more, and I know the difference.  A minor example is that I make more mistakes in typing, for example I switch "their" for "they're" and vice versa.  This is a mistake that I used to find utterly mystifying, and now I am doing it.

The other day I updated my lifetime river log with the rivers I have run this year.  I've done 20 new rivers around Oregon this year!  But the shocker finding was that one day in July when I went paddling on the Lower Wind, I could not remember what had happened when I logged the day.  All I remembered at the time (a few days after the actual day when I logged it), was that I had planned to go paddling with Todd.  I did not remember where we went or what happened.

What happened that day was that I hit my head, again, and had short term memory loss as a result.  I have had many traumatic brain injuries over the years, from biking, skiing, and kayaking.  This is the reason that I want to donate my brain for research.  I suspect that my brain will prove that recreational sports participants can also suffer from CTE = chronic traumatic encephalopathy.  It's not just for football players anymore.

On that day I flipped over at the top of a rapid known as the Flume, and was battered on my head and shoulders as I floated through the rapid upside down.  I was afraid to try to roll up because getting in position to roll puts you in a more open and vulnerable position, so I "went turtle" which in this case simply means to tuck tightly under the boat and get my elbows in so nothing gets broken.   I rolled up at the bottom of the rapid and was dazed but otherwise OK.  And yes, for you who do not know me, I was wearing a top notch helmet.  There is no helmet that can protect your brain from the knocking it takes when your whole head is getting walloped around.

This was the third time I'd floated through that particular rapid upside down.  It is a steep, fast, shallow and rocky rapid....brutal, really.  One of my three upside down runs I didn't hit a thing.  Twice I've been beaten silly.  I vowed after this day to not run that rapid at low water anymore.  It's much easier at higher flows and that is the only time I will attempt it.  Unfortunately the portage is difficult and dangerous too... so I may not go on the Lower Wind as much anymore.  Too bad because I do love the waterfalls.

Something else happened that day.  I've thought of it many times since my memory of the day returned.  At the end of the Lower Wind run there are four major drops, three falls and one slide, not in that order. We'd run the first 12 foot falls without incident and were running the tallest single waterfall, about 18 feet vertical.  It's so high that you can't see if the person ahead of you made it, so we just wait a few seconds between boats and then go.  Todd went ahead of me and I waited probably eight seconds, then committed to the drop.  When I crested the horizon line and could see my landing zone at the foot of the falls, he was swimming in it.

He had plunged too deep in the hole below the drop, gotten caught and held, and wet exited from his kayak in the hole.  It took him a while to surface and start floating downstream.  When I saw him I was already mid-air and headed straight for him.  I was afraid that the bow of my kayak would plunge into the water and hit him in the abdomen, rupturing his organs and killing him. That didn't happen.  Thankfully I'd hit a good enough boof from the top that my bow skipped off the surface of the water and I went right over his head.  But the trauma of believing that I was about to kill Todd has not left me.  I am going to require a better signalling system for running blind drops from now on.  I need to know that the landing zone is clear.  We have had trouble at this drop before and still we are too casual about it.
liveonearth: (moon)

Anacoluthon per wikipedia = an unexpected discontinuity in the expression of ideas within a sentence, leading to a form of words in which there is logical incoherence of thought.  It's how Trump talks, and can be useful for putting people in a stream of consciousness mode: less analytical, more suggestible.  Plural = anacolutha.  I've been studying up on hypnosis.  =-]

https://en.wikipedia.org/wiki/Anacoluthon


**first use of tag: hypnosis

liveonearth: (moon)
Just the other day a young man came to a doctor for help with persistent headaches after a hard head hit.  He left with a prescription for Nat sulph 1M.  What's that you ask?  That's sugar pills.  That's homeopathy, that's a substance so diluted that it isn't there, that's a treatment that has zero basis in science and plenty of mythology around it.  If you look online you will find plenty of articles supporting the use of homeopathy for brain injuries.  Check it out:

http://www.naturalnews.com/026057_injury_homeopathic_medicines.html#

http://www.britishhomeopathic.org/bha-charity/how-we-can-help/conditions-a-z/a-little-bump-or-a-major-injury/

https://www.northatlanticbooks.com/blog/unexpected-help-for-victims-of-traumatic-brain-injury/

http://homeopathyplus.com/brain-injury-homeopathy-can-help/

https://www.psychologytoday.com/blog/natural-remedies-emotional-health/201302/healing-cognitive-and-emotional-effects-head-injuries





Traumatic brain injuries are very common in athletes and soldiers, and many of them go unreported and untreated.  Sure, there's a lot of media buzz these days about TBI because they've discovered that some football players and boxers have dramatically shrunken brains, and depression and tremors later in life, because of something they call CTE, chronic traumatic encephalopathy.  Those words just mean longterm brain injury from being bashed around.

If you go to your doctor for a TBI, and it's a conventional doctor, he's likely to tell you rest will fix it.  Specifically no reading or screens for a week or so, no work if you can get out of it.  He's likely to tell you that it will pass on its own.  Sometimes it does.  That's when homeopathy "works", of course, when the condition it is supposed to treat would have passed on its own without treatment.  But what about those cases that are more severe?  What if rest and sugar pills aren't enough, and the brain really needs some help?  Both the homeopath and the conventional physician fail in that case.

There are good treatments for TBI.  There are doctors in the military who know them.  At a bare minimum people who've bashed their brains need lots of omega 3 fats and a clean, veggie rich diet.  There are herbs that have been shown to help a lot with brain recovery.  It's concerning that conventional doctors are so anti-botanical medicine that they don't even study up on that.  When are we going to get real about what works and what doesn't, instead of walking around parroting what we've been told?
liveonearth: (Spidey: come into my parlour)

I call it conscious realism: Objective reality is just conscious agents, just points of view. Interestingly, I can take two conscious agents and have them interact, and the mathematical structure of that interaction also satisfies the definition of a conscious agent. This mathematics is telling me something. I can take two minds, and they can generate a new, unified single mind. Here’s a concrete example. We have two hemispheres in our brain. But when you do a split-brain operation, a complete transection of the corpus callosum, you get clear evidence of two separate consciousnesses. Before that slicing happened, it seemed there was a single unified consciousness. So it’s not implausible that there is a single conscious agent. And yet it’s also the case that there are two conscious agents there, and you can see that when they’re split. I didn’t expect that, the mathematics forced me to recognize this. It suggests that I can take separate observers, put them together and create new observers, and keep doing this ad infinitum. It’s conscious agents all the way down.

--Donald Hoffman, Professor of cognitive science UC, Irvine,

http://www.theatlantic.com/science/archive/2016/04/the-illusion-of-reality/479559/

liveonearth: (old books)

I have been increasingly conscious, for the last 10 years or so, of deaths among my contemporaries. My generation is on the way out, and each death I have felt as an abruption, a tearing away of part of myself. There will be no one like us when we are gone, but then there is no one like anyone else, ever. When people die, they cannot be replaced. They leave holes that cannot be filled, for it is the fate — the genetic and neural fate — of every human being to be a unique individual, to find his own path, to live his own life, to die his own death.
--Oliver Sachs
(New York Times, Opinion, “Oliver Sacks on Learning He Has Terminal Cancer,” Feb. 19, 2015)


This from the FFRF blog: )

*Created tags for reason and humanism.

SOURCE
http://ffrf.org/news/blog/item/23735-remembering-oliver-sacks

liveonearth: (neuroactive substances)
If you live and Portland and haven't picked up a copy of this month's Willamette Week (free news weekly, online here: http://www.wweek.com/portland/index.php), this issue is likely to get snapped up. They've named it the 420 Issue and it is all about the businesses and culture incurred by the recent legalization of cannabis in Washington and soon Oregon. What struck me initially is the amount of wordplay around the subject, and the generation of witty new phrases, words and hashtags that accompanies the surge in businesses and products containing cannabinoids. There is great excitement about the new availability and openness that comes with legalization.

I for one am OK with recreational and medical use. I think that the risks to society of adults using cannabinoids are fairly minimal. It certainly doesn't make people drive dangerously the way alcohol does. It does have a whole set of risks that aren't covered in this issue, and that really need to be kept high in our awareness as this drug becomes widely acceptable.

One risk that is coming into focus these days is of extreme overdoses. Back when folks just inhaled smoke, coughing stopped them from partaking too much. Vaporizers now make inhalation gentler and it is easy to overdose when consuming edibles. With either method you can't tell how much intoxicant is in there. With humans ingeniously extracting and concentrating the active principles, it could be very strong, or contaminated with solvents. With edibles the effect takes time to kick in. It is terribly easy to overdose for folks who are experimenting for the first time, and who have no tolerance at all.

The conventional media take on overdose--blaming it for many deaths and claiming that it is deadly--is probably overblown. It takes a massive amount of pot to kill, perhaps more than anybody is likely to actually reach because unlike opioids it is so unpleasant getting there. It is however a relative unknown: having been illegal for so long, we don't have scientific studies about overdose. We hardly have science to justify all the medical uses that have already been approved. We are going to find out now.

Another risk is incurred by the fact that edibles make the drug palatable to people who would never smoke it. It is tempting to children as candy. There is the danger that children, teens and early 20-somethings will enjoy sugary yummies containing cannabinoids and permanently alter their brain development. Later on in life there is still a brain changing effect, but in early life when the brain is still forming, the effect can be severe.

On top of these new risks due to the availability of edibles, there is the old risk of respiratory injuries resulting in sinusitis and bronchitis, and risk of more dangerous conditions like pneumonia and COPD. There is also the fact that marijuana increases heart rate significantly in most individuals. Folks who already have hypertension or heart palpitations might give themselves a heart attack.

I suppose my main message in the light of all this 420 excitement is BE CAUTIOUS and PROTECT YOUR CHILDREN because there is a lot we don't know. I believe in freedom and individual discretion as most Americans do, and I also know that people can be terribly foolish and injure themselves and others, especially when intoxicants are involved. I cannot protect the whole world from poor choices, but I do hope that this warning is heard widely. Please take care of each other and if you are going to play with the newly legalized products, start very small.
liveonearth: (moon)
I’m reminded of a case study that describes an individual who had come to associate sexual arousal with being covered in insects. As a child, that individual had been locked into closets for unimaginable amounts of time, and during those times, bugs would frequently fill the space and crawl on him. The child, trying to seek some sort of escape from the reality of his experience, found comfort only in sexual release—even though he was too young to even know what sex was or meant. His body knew only that it felt good, and it provided the only possible escape available to him. In his mind, those associations became, quite literally, wired together.
--Roger Thompson | The Atlantic | December 19, 2014
http://www.theatlantic.com/education/archive/2014/12/times-up-for-timeout/383897/

*new tag: "kink"
liveonearth: (moon)
Notes from the article:
Cannabinoids take the brain by STORM
Wed, 12/10/2014 -- Holly Brothers PhD
http://www.sciguru.org/newsitem/18095/cannabinoids-take-brain-storm
notes )
liveonearth: (moon)
If you tell a lie big enough and keep repeating it,
people will eventually come to believe it.

--Joseph Goebbels, Nazi propagandist
liveonearth: (bipolar_express)
The DSM, of course, is the list of diagnoses written by and for psychiatrists who are dispensing pharmaceuticals which are covered by insurance. The DSM does not consider the possible causes of the disorders listed, nor allow for the possibility that simple lifestyle changes might be adequate to "cure" a disorder. The book is used to authorize the mental health professional to dispense psychoactive medications. No conflicts of interest there (ahem).

The National Institute of Mental Health (NIMH instead of just NIH) has decided that the basis of the DSM is not scientific enough, and it is not using those diagnoses as a foundation for ongoing research. The new Research Domain Criteria (RDoC) project to is intended to transform diagnosis by incorporating genetics, imaging, cognitive science, and more to create a new classification system. The new system of knowledge will be based on biology as well as symptoms, and will consider specific brain circuits, genetics, and experiences without regard for DSM categories. In fact the NIH is looking to support research projects that look across or subdivide current categories.

This is superb and hopeful to every person who has even been stuck with a diagnosis that didn't fit, or medicated when a simpler solution wasn't even entertained. My congratulations to the NIH for being independent enough to seek the truth.

SOURCE
http://www.nimh.nih.gov/about/director/2013/transforming-diagnosis.shtml
liveonearth: (Volume 11 spinal tap)
OK, maybe that's a little exaggerated, but basically any drug causes a dopamine surge that changes your brain such that the rewards of normal life don't seem good enough anymore. This study actually found that pot smokers have a bigger nucleus accumbens (the brain area associated with pleasure, reward, and reinforcement learning). They say that 19 million Americans have smoked pot recently. That's a lot.

Here's the article:
http://www.washingtonpost.com/news/morning-mix/wp/2014/04/16/even-casually-smoking-marijuana-can-change-your-brain-study-says/
text )
liveonearth: (moon)
Left-handed people really do have different brains and genes from right-handed people. Yet left-handed people are almost never included as study subjects in scientific research. Therefore in an article in Nature Reviews Neuroscience, Roel Willems and his colleagues from the Donders Institute and Max Planck Institute in Nijmegen call for more research into left-handed people. The article was published online on 12 February 2014.

Left-handed people are rarely included as study subjects for brain or genetic research because the differences with right-handed people cause noise in the final results. However, left-handed people form about ten percent of the entire population and their brains and genes contain interesting information about the functioning of both halves of the brain as well as about several psychiatric disorders. 'Research into left-handed people is therefore interesting because of the noise they cause', thinks neuroscientist Roel Willems from the Donders Institute for Brain, Cognition and Behaviour at Radboud University Nijmegen. With the opinion article he calls upon his fellow researchers to stop excluding left-handed people from studies.

Missed chance for the neurosciences

'One of our studies from 2009 clearly shows why research into left-handed people is so vital', says Willems. 'According to the textbooks, facial recognition takes place in the right half of the brain. Our research revealed that the same process takes place in both halves of the brain in the case of left-handed people, but with the same final outcome. That is a fundamental difference. And left-handed people might process other important information differently as well. The minimal amount of research into this is, in my view, a missed chance for the neurosciences.'


SOURCE
http://medicalxpress.com/news/2014-02-scientists-urged-excluding-left-handed-people.html
liveonearth: (TommyLeeJones_skeptical)
The National Institutes of Health, 10 large drug companies and seven nonprofit organizations announced an unconventional partnership on Tuesday intended to speed up development of drugs to treat Alzheimer’s disease, Type 2 diabetes, rheumatoid arthritis and lupus.

During the course of a five-year, $230 million effort, the participants will share data in regular conference calls and meetings, working together to determine which findings are likely to lead to effective treatments. They will make their findings and data publicly available.


...What concerns me about this is the emphasis on drugs. There are better ways to adjust physiology than taking in foreign substances. And there are more useful things we could study. Like food, and exercise, and how to they affect our biochemical and electrical mileau. Sex, we should throw more money at studying sex and how it affects neurotransmitters. On the effects of chewing gum and on understanding the endocrinology of sexual preference. And on why our hearts slow down as we age, and a million other questions. I'm just curious: I really want to know the answers. I wish that the money spent on medical research was directed more by altruism and less by profit motive.

SOURCE
http://www.nytimes.com/2014/02/05/health/nih-joins-drug-makers-and-nonprofits-on-stubborn-diseases.html
liveonearth: (moon)
Notes on an online lecture by David Perlmutter MD on the effects of grains in the diet on brain function... his book on the same subject is just out.
notes )
liveonearth: (House religion psychosis)
We are all, to some extent, crazy. If you come to know any human being well enough, you eventually gain access to the basement where the traumas and wounds and deprivations are stored; rummage in there for a while, and you begin to understand the neuroses and fixations that shape his or her personality. The successful, reasonably happy people I've known are nuts in a way that works for them. Those who struggle and suffer fail to turn their preoccupations to some meaningful use. Next week, the American Psychiatric Association release the latest version of its bible of mental illnesses, the DSM-5, which catalogs about 300 categories of crazy. Critics of all kinds have lined up to assail this dictionary of disorders as subjective and lacking in scientific validity--assembled primarily to justify the prescribing of pills of dubious value.

About 50 percent of the population, the APA admits, will have one of its listed disorders at some point in their lives. Shy, like Emily Dickinson? You have "avoidant personality disorder." Obsessed with abstractions and numbers? You have "autistic spectrum disorder," like Isaac Newton. Suffer form "narcissistic personality disorder," with some hypersexuality thrown in? You must be a politician. To be skeptical of these neat categories isn't to deny that minds get broken, stuck, or lost, and need help finding their way out of misery. But psychotherapy remains an art, not a science; there is no bright line between nuts or not. If you're an old lady who lives amid piles of newspapers and personal treasures, you have "hoarding disorder." If you're a CEO who exploits sweatshop labor to pile up countless billions, you're on the cover of Forbes.


--William Faulk (editor-in-chief) in The Week, May 24, 2013 issue.
liveonearth: (moon)
It sounds cruel, but survivors laugh and play, and even in the most horrible situations--perhaps especially in those situations--they continue to laugh and play. To deal with reality you first much recognize it as such...and play puts a person in touch with his environment, while laughter makes the feeling of being threatened manageable.

...Laughter stimulates the left prefrontal cortex, an area of the brain that helps us to feel good and be motivated. That stimulation alleviates anxiety and frustration. There is evidence that laughter can send chemical signals to actively inhibit the firing of nerves in the amygdala, thereby dampening fear. Laughter, then, can help temper negative emotions.


Laurence Gonzales in Deep Survival, page 41.

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liveonearth

May 2025

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