liveonearth: (rock OUT)
A new study shows that patients with mild cognitive impairment (MCI) do not progress to dementia if they drink enough coffee! Gotta love it. I'm going to start drinking a whole pot, by golly. The researchers in this study think that it's the caffeine, and not the anti-oxidants, that has the anti-dementia effect, but according to mouse studies, it has to be coffee. Those patients with a little MCI who java it up enough to have a plasma caffeine level of 1200ng/mL did not go into dementia. 100%. The caffeine appears to inhibit an enzyme used in the manufacture of beta amyloid! They're also tracking cytokines in the plasma and finding that there's a particular profile assorted with conversion to Alzheimer's disease (low IL-6, IL-10, and G-CSF). In the future we might consider testing for those cytokines to detect impending dementia in healthy patients.
notes!! )
liveonearth: (moon)
Twenty eight percent (28%) of US households are now just one person living alone. This is the most ever. These singles are the biggest spenders, contributing 1.9 trillion to "the economy" each year. (According to The Week 2/10/12 which is in turn quoting Fortune magazine)

And another factoid from the same source: the number of US prisoners age 65 and over has increased 63% between 2007 and 2010. I guess we're keeping them put away so long that now they need more medical care, and it's becoming an issue. The total number of prisoners has been flat for that same period.
liveonearth: (looks like house to me)
A new study has been published in the November issue of the British Journal of Psychiatry (Br J Psych. 2011;199:386-390). This is the first longitudinal study showing brain effects of marijuana; it reduces the volume of the thalamus in folks age 16-25 who are well but have a family history of schizophrenia. The reduction is greater on the right side.
more notes )
liveonearth: (Default)
http://www.telegram.com/article/20110710/NEWS/107109970/1237

Makes the case that as we age, we should get our ducks in a row for the possibility that we ourselves might not make the best decisions about money in our old age.
liveonearth: (moon)
Neuroplasticity wanes with age. It gets harder to learn. It gets harder to unlearn. It gets easier to do the same thing you have done the whole time and to expect the same response. This process gets more and more concentrated until suddenly you are demented. You don't know that it's 2010, almost 2011, suddenly you're stuck in 1984. Suddenly everyone is your honey, or your special version of the boogey man, and you can't imagine anything other than the 100 stories that are still active in your mind. When somebody reminds you of something, you are off to the races, galloping down memory lane. The right turn or left split or U-turn spot are not seen, only that familiar story with all its referents. Santa clause playing bagpipe riding a unicycle is not even there.
more )
liveonearth: (Default)
(Reuters) - People with insulin resistance and type 2 diabetes are more likely to develop plaques in the brain associated with Alzheimer's disease, researchers in Japan reported on Thursday.

The study involved 135 elderly participants in the town of Hisayama, Fukuoka prefecture, who had their blood sugar levels checked several times at the start of the study. They were then monitored for signs of Alzheimer's disease for 10 to 15 years.

After they died, researchers conducted autopsies on their brains and found plaques, particularly in those who had high blood sugar levels while they were alive.
more )
liveonearth: (Default)
Alzheimer’s Disease and Curcumin: an Update
June 15, 2010
Jacob Schor, ND, FABNO
Denver Naturopathic Clinic
curcumin, DHA (docosahexanoic acid), and alpha lipoic acid )
liveonearth: (Default)
Well so we already knew that drugs that increase serotonin levels decrease bone density over time. Medscape's new report says that osteoporosis is associated not just with SSRIs, but with benzos and some mood stabilizers other than lithium. Tricyclic antidepressants are protective for bones, but they have other gnarly side effects.

They've also found that mental disorders themselves have significant bone correlations. Dementia, schizophrenia and alcohol dependence are associated with reduced bone density. Depression is associated with less osteoporosis---which makes sense if you think that a lot of depression is due to low serotonin levels. Bipolar disorder and drugs other than alcohol were not found to have any correlation with osteoporosis.

Aside: FDA has released new warning that Tramadol (an opioid) increases suicide risk.
liveonearth: (Default)
ALUMINUM
is a light metal
is in some vaccines (Hep A&B, DTaP, Hib, Pneumocc, HPV/Gardasil, et al)
is not in all (read package inserts)
is a known toxin with no beneficial biological function
impairs glutathione synthesis
impairs your body’s ability to excrete mercury
is used as adjuvant in vaccines without good research proving that it does what they say it does
FDA limit of 850mcg/vaccine is based on commercial usage and not on safety
no limit on how many vaccines are given at the same time
no different between infant and adult max dose
doses given to children in US have more than doubled since the 1980's
notes from Mercola interview of Dr Ayoub about aluminum toxicity, vaccines, autism )
liveonearth: (Default)
Between 2003 and 2005 there was a huge increase in the off-label use of prescription antipsychotic drugs on seniors with dementia. The population most at risk of being prescribed these meds is old folks in nursing homes. Better ask what that drug is that they put your parents on, especially if they can be little unruly. In 2005 the FDA came out with an advisory and started requiring black box warnings about the risks of increased strokes, diabetes, and sudden death. From 2005 to 2008 the off-label use decreased 50%. The FDA did something useful! But still, a lot of seniors may be inappropriately prescribed these meds.

SOURCE
http://www.medscape.com/viewarticle/715257?src=mpnews&spon=12&uac=89474MT
liveonearth: (Default)
High Leptin Levels May Protect Against Dementia
by Pauline Anderson for Medscape
December 15, 2009
notes )

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