liveonearth: (Default)
WHITE CELL NEOPLASMS
--malignant proliferation dz is the most imp disorder of WBC
--two main types: lymphoid and myeloid
--lymphoid neoplasms incl: Hodgkin's lymphoma and non-Hodgkin's lymphoma
--myeloid neoplasms incl: proliferation of abn hematopoietic cells (AML, ALL, CML, CLL), myelodysplastic syndromes (MDS), histiocytoses, plasma cell dz (multiple myeloma)
--histological exam (biopsy) of lymph nodes or other involved tissue required for Dx
--in most lymphoid neoplasms, antigen receptor gene rearrangement precedes transformation, can be used to distinguish reactive and malignant lymphoid proliferations
--majority of lymphoid neoplasms are of B-cell origin (80-85%)**
--cause immune abnormalities
from pathology notes )
liveonearth: (Default)
The "rare syndromes" that are associated with multiple lipomas, according to my minor surgery notes, are "Gardner's syndrome and two benign conditions--multiple symmetrical lipomatosis and Dercum's disease. In the latter, the lipomas are painful". I had to look it up because my sister's husband is covered in them, and because in the last 2 years I've begun to develop them all over my body including strange locations such as over the biceps femoris tendon in my posteriolateral popliteal area--very small so far--I suspect a hormonal etiology. More occur in women after menopause, and familial types onset at adolescence. With some types there is an increased incidence of breast, endometrial and thyroid cancer. Sounds like it may be related with estrogen dominance. This would be supported by the increased incidence with obesity. There is also an association with multiple endocrine neoplasia type I (lipomas and pancreatic, parathyroid, pitutitary tumors). The list of hormonal associations increases the deeper I dig. There are also fat deposits associated with spina bifida. Looks like nobody has studied hormones in lipomatosis patients, but based on my short survey I have just now formed the opinion that is expressed in the title of this entry.
notes: fyi, when something is marked with triple questionmarks it means that the source is not convincing and I kinda doubt it, but I'm recording it for future reference anyway )
liveonearth: (Default)
--aka sarcoid from Gr "sark" and "oid" means flesh-like
--Besnier-Boeck disease
--immune disorder krkrized by non-caseating granulomas usu in lungs or lymph
more )
liveonearth: (Default)
Aka Lymphoid neoplasms, lymphomas a heterogenous group of neoplasms that arise in the lymphatic and reticuloendothelial (RE) systems.
more )

Profile

liveonearth: (Default)
liveonearth

May 2025

S M T W T F S
    123
45678910
11121314151617
1819202122 2324
25262728293031

Syndicate

RSS Atom

Most Popular Tags

Style Credit

Expand Cut Tags

No cut tags
Page generated May. 29th, 2025 09:11 pm
Powered by Dreamwidth Studios