liveonearth: (Default)
--second messenger = diffusable signaling molecule produced or secreted after signal is received
--molecule activates effector proteins inside cell-->cell response to signal
--can be synthesized/released and broken down again in specific rxns
--production, storage, and destruction can be localized
this stuff is pretty hazy so far, clarification much needed )
liveonearth: (Default)
What does pituitary mean, from the Latin? (think onomatopoeia...)
to spit mucus
ptuo = to spit, pituita = mucus

What do you call a hormone that acts on neighboring cells?
paracrine

Are pituitary hormones steroid, steroid type, or peptide hormones?
peptide, all of them are

What do you call the loss of lateral visual fields?
bitemporal hemianopsia

Damage to what part of the pituitary causes diabetes insipidus, and which hormone is lacking?
self quiz from SSL's notes )
liveonearth: (Default)
ScienceDaily (Nov. 28, 2008) — Obesity gradually numbs the taste sensation of rats to sweet foods and drives them to consume larger and ever-sweeter meals, according to neuroscientists. Findings from the Penn State study could uncover a critical link between taste and body weight, and reveal how flab hooks the brain on sugary food.
notes )
liveonearth: (Default)

When it gets hot, I like to go jump in the river. The Oregonians think the river is too dangerous, too polluted. I was repeating this viewpoint minutes ago, while sitting in a kiddy pool in my back yard with one of the young reporters who lives downstairs. She told me that in late July there was a toxic algae bloom in the Tualatin River. The Tualatin flows into the Willamette at Lake Oswego.

Public Health officials advised boaters and swimmers to stay away from it, and put up signs to warn people to keep out and keep their animals away. The USGS reports that 8-9 dogs/year die of drinking blue-green algae infested water.
the toxins they aren't reporting about because they are so scarey )
liveonearth: (Default)
Study Questions:
1. Does having an immune response to a colon tumor preclude you from getting lung cancer? Why or why not?
2. What happens if you systemically and non-specifically turn on all of your T cells at once?
3. What are TSAs?
4. How does a DC vaccine for cancer work?
5. Why can people often fight off virally induced tumors but not spontaneous tumors?
6. Name one way that viruses that cause tumors evade the immune system.
7. Which cells of the immune system have receptors for neurotransmitters?
8. What effect do glucocorticoids have on the immune system?
9. Name 3 problems that make it difficult to do PNI studies.
answers and some info about unconventional cancer research and treatments )
liveonearth: (Default)
Practiced yoga at the school this morning. Was up before 6am. Mind is going. I believe that there is a biological link between the strength of the core and the experience of BEING. Notice how all the really brilliant, centered people all sit up so straight? Walk so tall? Having a strong core and an aligned spine links, I think, into our limbic systems, into the most primitive part of our brains. Walking resets the emotions. Terry male says I have an overactive amygdala which is what causes me to have religious experiences. Brons says the amygdala is all about fear and aversion, anxiety, fear conditioning, antinociception and autonomic adjustments. Religious experiences, fear and aversion. I wonder where awe falls into that mix.
I am fascinated by all my coursework right now but especially the brain material from Brons )
liveonearth: (Default)

Ventral tegmental dopamine neurons respond only to UNPREDICTED REWARDS. When the goodie is predictable, those particular dopamine cells stop firing. They's the ones that say "Oh YEAH" to something one discovers as enjoyable and satisfying. Smoking a cigarette fires those cells even when it's not unpredicted, it provokes that Oh YEAH chemistry every single time you light up.

It's the dopamine release in the nucleus accumbens that stengthens the links between the stimulus and the wanting. Wanting and liking are not the same.

boring to most, notes from organ systems class and later added notes from Intoxicating Minds, this reminds me of the wampus game on the old obsorne PC's, draw your twenty rooms and start sketching in the links )
liveonearth: (Default)
ON DRUG MECHANISMS
print chart from this page: http://www.e-epilepsy.org.uk/pages/articles/show_article.cfm?id=127

from Mechanisms of action of anti-epileptic drugs
Andrew Fisher, Matthew C Walker and Norman G Bowery*

Department of Clinical and Experimental Epilepsy, Institute of Neurology, UCL, London, and *Department of Pharmacology, University of Birmingham Medical School, Birmingham

THREE main mechanisms by which current drugs appear to produce their anticonvulsant activity:
1) Modulation of intrinsic membrane conductances, primarily voltage-gated cationic channels
2) Suppression of excitatory amino acid-mediated synaptic transmission
3) Enhancement of GABAergic inhibitory synaptic transmission, via post-synaptic receptor modulation, inhibition of GABA metabolism or blockade of GABA transport.
voltage gated sodium and calcium channels, GABA, glutamate and drugs )
liveonearth: (Default)
SGA welcomes Julia Ross!
Author of The Diet Cure & The Mood Cure
Monday March 31st
9am-1pm
Mood & Alternatives to Antidepressants
This is FREE
for NCNM students!
so I went )
liveonearth: (Default)
Over the weekend I attended a conference called Transforming the Mind, and this piece was played as the grand finale: http://www.ted.com/talks/view/id/229

Jill Bolte Taylor is an excellent storyteller and the story is worth hearing. Jill is also a neuroanatomist. She had a stroke one morning and observed her own brain shutting down. The blood vessel popped in the left hemisphere of her brain, and crowded out her language centers and more, leaving her with right brain hemisphere functions. She experienced Nirvana, or what some might call a near death experience.....but it is better to hear her tell the tale. I hope you enjoy!
liveonearth: (Default)
I believe we're talking about NEUROtransmitters, here, but Brons is abstruse. Small molecule transmitters are fast acting in acute sensory and motor responses of nervous system. Both direct and indirect. Removed from synapse by diffusion, enzymes or reuptake. Drugs often work by affecting synthesis or removal of transmitters. The action of a neurotransmitter is determined by its receptors. One neurotransmitter may affect different types of receptors each with a different action.
Lots more )
liveonearth: (Default)
Gardeners already know this.
New research in the UK links dirt to seratonin:
http://news.bbc.co.uk/2/hi/health/6509781.stm

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