liveonearth: (Default)
A group of clinically and biochemically diverse diseases characterized by proliferation of ONE clone of plasma cells normally engaged in immunoglobulin production. PCD's account for 15% of WBC neoplasms. Typified by the presence of a monoclonal Ig or polypeptide subunit (fragment) in serum or urine. Monoclonal immunoglobin in the blood is referred to as "M component".

All are composed of terminally differentiated B cells, arise in the bone marrow, secrete whole Ab's or immunoglobulin fragments, cause bony destruction. Patients present with pain dt pathologic fractures.

Five types including related disorders:
1) Multiple Myeloma
2) Waldenstrom's macroglobulinemia
3) Heavy Chain dz
4) Primary or immunocyte-associated amyloidosis
5) MGUS = Monoclonal gammopathy of undetermined significance. MGUS is common in elderly pts and has no signs or symptoms.
Expandmore )
liveonearth: (Default)
MYELOPROLIFERATIVE DISORDERS:
--caused by clonal expansion of pluripotent stem cell in bone marrow (BM) causing abnormal production of erythroid, myeloid, andmegakaryocytic precursors
--reflected in PB smear and CBC results
--multiple BM cell lines usu affected, but one cell line may dominate
--TYPES:
1. Polycythemia Vera
2. Myelofibrosis
3. Essential Thrombocythemia
4. Chronic Myelogenous Leukemia (CML)
Expandspecifics on the first three, the fourth is in leukemia post )
liveonearth: (Default)
GENERAL NOTES:
--myeloid neoplasms incl: leukemias, myelodysplastic syndromes, histiocytoses, plasma cell dz
--malignant neoplasm of blood-forming tissue-->marrow replacement
--decreased apoptosis of cells --> increase in #'s
--ETIO: HTLV-1, oncogenes (p53), envir: EMF, benzene, radiation, x-rays, chemo drugs
--malignancy is found in 50% of pts with unexpected increased platelet counts (esp CML)
--acutes have immatures in PB, esp blasts
--chronics have more mature cells
--over 30% blasts in marrow usu means leukemia
--best way to differentiate btw B-cell and T-cell types: immunophenotyping
Expandnotes on four kinds of leukemia and myelodysplasia (pre-leukemia) )
liveonearth: (Default)
If you die 5 years and 1 day after a cancer diagnosis, what are you?
Expandnotes from Dr Thom's lecture )
liveonearth: (Default)
Thoracic Outlet Syndrome Tests have poor validity, as there is a false positive rate of 53-92%. So if someone does this test on you and you have a positive result (usually a + is elicited pain/numbness/tingling or loss of a pulse), it doesn't mean anything for sure. Positive tests should be "assessed cautiously".
Expandmore )
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COMMON NAMES: flaxseed, linseed, alashi, brazen, flachssamen, flax, leinsamen, hu-ma-esze, linen flax, lini semen, lino, lino usuale, lint bells, linum, keten, etc.
Expandmore )
liveonearth: (Default)

Passiflora = Passion Flower, looks passionate to me
grows on a vine
species: incarnata, edulis (pictured), coerulea
family: Passifloraceae
Expandnotes )
liveonearth: (Default)

FAMILY: Gentianaceae
MORE SPECIES: Gentiana calycosa is native to the PNW. Varieties found all over the planet.
COMMON NAMES: bitter root, bitterwort, gall weed, gentiana, gentianae radix, pale gentian, stemless gentian, yellow gentian, wild gentian, quin jiao
Expandmore )
liveonearth: (Default)
Phew. Seems like I am constantly on the edge, but I keep passing, so I guess I'm doing something right. I even got honors in a couple classes, including the one in which I was shaking so hard that it was really tough to draw blood. Phew. Now I'm officially an ND3. I am still on the 4 year track, slated to graduate in 2011 with a lot of clinical experience already under my belt. I can't relax yet. I'm studying biochemistry today, in preparation for the Basic Science Boards. August 5. I'll get to relax after that.

I will be taking the first ever case-based NPLEX exam for ND's. What this means is that instead of having five sections (pathology, biochemistry, anatomy, physiology, microbiology) it will have many cases each with 5 questions relating to the case. This makes it more interesting to me. I am studying biochemistry by looking up metabolic dysfunctions and understanding their chemical pathogenesis.
Expandbiochemistry nerdiness: mucopolysacchariosis nutshell )
liveonearth: (Default)
STUDY GUIDE FOR FINAL EXAM – BOT MED II SPRING 2008
(To be reviewed in class, week 11, 8 am)
Expandnotes from the top of my head and Craig's )
liveonearth: (Default)
Be prepared to perform grade IV - V manipulations from this list:
1) prone rib elevation
2) prone rib depression
3) upper thoracic rotation or extension (bedside move)
4) upper rib posterior to anterior manipulation prone (bedside move)
5) supine flexion ("anteriority" move)
6) alternative positioning supine flexion ("anteriority")
7) supine rotation
8) supine rib posterior to anterior manipulation
Expandwe're learning to manipulate spines and ribs from chiropractor Agresta )

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