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Coagulation, Vitamin K and Clotting Factors
What is the most common hereditary clotting problem?
--Von Willebrand's Dz (factor is absent or abnormal, many varieties)
What do you call an inactive enzyme precursor in the clotting cascade?
--a zymogen
What do you call a coagulation deficiency from to a deficiency of Factor VIII due to an X-linked recessive gene?
( answer and more self-quiz )
--Von Willebrand's Dz (factor is absent or abnormal, many varieties)
What do you call an inactive enzyme precursor in the clotting cascade?
--a zymogen
What do you call a coagulation deficiency from to a deficiency of Factor VIII due to an X-linked recessive gene?
( answer and more self-quiz )
Sunshine Beats Cancer: research still coming in
The Canadian Cancer Society is now recommending vitamin D for all adults based on a study that was performed in Nebraska. Let's see how long it takes the US to catch up.
http://v.mercola.com/blogs/public_blog/New-Evidence--Sunshine-DOES-Slash-Your-Cancer-Risk-20485.aspx
http://www.ncbi.nlm.nih.gov/sites/entrez?orig_db=PubMed&db=PubMed&cmd=Search&term=Am.%20J.%20Clin.%20Nutr.%5BJour%5D%20AND%202007%5Bpdat%5D%20AND%20Lappe%20J%5Bauthor%5D
http://www.theglobeandmail.com/servlet/story/RTGAM.20070608.wvitaminD08/BNStory/specialScienceandHealth/home
( more )
http://v.mercola.com/blogs/public_blog/New-Evidence--Sunshine-DOES-Slash-Your-Cancer-Risk-20485.aspx
http://www.ncbi.nlm.nih.gov/sites/entrez?orig_db=PubMed&db=PubMed&cmd=Search&term=Am.%20J.%20Clin.%20Nutr.%5BJour%5D%20AND%202007%5Bpdat%5D%20AND%20Lappe%20J%5Bauthor%5D
http://www.theglobeandmail.com/servlet/story/RTGAM.20070608.wvitaminD08/BNStory/specialScienceandHealth/home
( more )
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On FLU prevention, by Paul Berger (ZACES formula, herbs)
from the Medical Herbalism Eletter
Periodically published by the North American Institute of Medical Herbalism
Contact them at http://medherb.com or http://naimh.com
December 2008
( article text )
Periodically published by the North American Institute of Medical Herbalism
Contact them at http://medherb.com or http://naimh.com
December 2008
( article text )
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Vitamin D: increases glutathione, induces glioma apoptosis
New data shows that vitamin D has more biochemical actions that anticipated:
--inhibits the synthesis of inducible nitric oxide synthase
--increases intracellular glutathione levels-->helps remove mercury & other toxins from your body
--could be used to Tx neurodegenerative and neuroimmune diseases
--induces glioma cell death-->good for management of brain tumors?
According to Dr. Cannel, founder of the Vitamin D Council, in an interview:
--vitamin D is not a vitamin, but rather the only known substrate for a powerful repair and maintenance steroid hormone that is involved in numerous functions of your body and organs
--like all steroid hormones vit D regulates your body by turning your genes on or off
--you have about 2,000 genes that are directly influenced by vitamin D
SOURCES
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T3K-45BCJ53-7&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=36fe7df09fbacd4b33fe816072a1793d
http://articles.mercola.com/sites/articles/archive/2008/12/04/how-sunshine-and-vitamin-d-can-help-you-eliminate-mercury.aspx
--inhibits the synthesis of inducible nitric oxide synthase
--increases intracellular glutathione levels-->helps remove mercury & other toxins from your body
--could be used to Tx neurodegenerative and neuroimmune diseases
--induces glioma cell death-->good for management of brain tumors?
According to Dr. Cannel, founder of the Vitamin D Council, in an interview:
--vitamin D is not a vitamin, but rather the only known substrate for a powerful repair and maintenance steroid hormone that is involved in numerous functions of your body and organs
--like all steroid hormones vit D regulates your body by turning your genes on or off
--you have about 2,000 genes that are directly influenced by vitamin D
SOURCES
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T3K-45BCJ53-7&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=36fe7df09fbacd4b33fe816072a1793d
http://articles.mercola.com/sites/articles/archive/2008/12/04/how-sunshine-and-vitamin-d-can-help-you-eliminate-mercury.aspx
Vitamin D: best source is sunlight, treats radiation poisoning
Mercola offers this article:
http://articles.mercola.com/sites/articles/archive/2008/11/25/why-sunlight-is-your-best-source-of-vitamin-d.aspx
He says that a study on people with repeated respiratory infections found that cod liver oil also contains vitamin A, and that vitamin D and A compete with each other metabolically, so if you have too much vitamin A in your vitamin D supplement, you are not getting as much use out of the D. "Vitamin A and vitamin D compete for each other’s function. For example, even the vitamin A in a single serving of liver can impair vitamin D’s rapid intestinal calcium response." Mercola calls the amounts of vitamin A in the supplements "detrimental".
A separate study from the New York City Department of Health and Mental Hygiene suggests that one form of vitamin D (calcitriol, aka 1,25-dihydroxyvitamin D) may be one of your body's main protections against damage from low levels of radiation. Calcitriol is the active form of vitamin D might be an appropriate protective agent before or after a low-level nuclear incident!! Calcitriol is involved in cell cycle regulation, hence affects proliferation, differentiation, encourages apoptosis and autophagy, and inhibits angiogenesis.
http://articles.mercola.com/sites/articles/archive/2008/11/25/why-sunlight-is-your-best-source-of-vitamin-d.aspx
He says that a study on people with repeated respiratory infections found that cod liver oil also contains vitamin A, and that vitamin D and A compete with each other metabolically, so if you have too much vitamin A in your vitamin D supplement, you are not getting as much use out of the D. "Vitamin A and vitamin D compete for each other’s function. For example, even the vitamin A in a single serving of liver can impair vitamin D’s rapid intestinal calcium response." Mercola calls the amounts of vitamin A in the supplements "detrimental".
A separate study from the New York City Department of Health and Mental Hygiene suggests that one form of vitamin D (calcitriol, aka 1,25-dihydroxyvitamin D) may be one of your body's main protections against damage from low levels of radiation. Calcitriol is the active form of vitamin D might be an appropriate protective agent before or after a low-level nuclear incident!! Calcitriol is involved in cell cycle regulation, hence affects proliferation, differentiation, encourages apoptosis and autophagy, and inhibits angiogenesis.
Canada about to make Vitamin C a prescription drug???
This makes me wonder. Mercola isn't sure what is going on either, but it's interesting to contemplate that one might be forced to get a prescription to get basic supplements....please let me know if you find out more.
http://articles.mercola.com/sites/articles/archive/2008/06/19/vitamin-c-about-to-be-made-illegal-in-canada.aspx?source=nl
http://ezinearticles.com/?Vitamin-C-Is-About-To-Be-Made-Illegal-In-Canada!-Nutritional-Supplements-Banned-In-Canada!-Bill-C-51&id=1174122
( text of ezine article behind cut )
http://articles.mercola.com/sites/articles/archive/2008/06/19/vitamin-c-about-to-be-made-illegal-in-canada.aspx?source=nl
http://ezinearticles.com/?Vitamin-C-Is-About-To-Be-Made-Illegal-In-Canada!-Nutritional-Supplements-Banned-In-Canada!-Bill-C-51&id=1174122
( text of ezine article behind cut )
Vitamin C notes
High doses of vitamin C are used to treat some infections and some cancers. How high is high? 3-4 g/day is considered high, but one doc takes 200g/day and is OK, so we don't really know what the top end is and why.
( short )
( short )
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Vitamin D and Sunshine
Goji berries (not the juice)
Raspberries
Blackberries
Blueberries
The berries above are the "sunscreen" that Mercola recommends. Yep, he recommends "internal" sunscreen in the form of antioxidants. He has lots to say about vitamin D in this article: http://articles.mercola.com/sites/articles/archive/2008/3/15/vitamin-d-in-your-skin.aspx
Raspberries
Blackberries
Blueberries
The berries above are the "sunscreen" that Mercola recommends. Yep, he recommends "internal" sunscreen in the form of antioxidants. He has lots to say about vitamin D in this article: http://articles.mercola.com/sites/articles/archive/2008/3/15/vitamin-d-in-your-skin.aspx
Biochemistry: Vitamins and Minerals
1. Vitamins: small, low molecular weight, organic mols required for normal function, most we don't synthesize, classified as fat or water soluble.
Which vitamins are derived from isopentenyl pyrophosphate? Vitamin A (terpene), D, E, K, cholesterol
( more )
Which vitamins are derived from isopentenyl pyrophosphate? Vitamin A (terpene), D, E, K, cholesterol
( more )
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Biochemistry: The One-Carbon Pool: Folate and B12 Metabolism
What are the carrier molecules for one-carbon groups?
biotin, tetrahydrofolate, s-adenosylmethionine (SAM)
( lots about vitamin B-12 and folate here )
biotin, tetrahydrofolate, s-adenosylmethionine (SAM)
( lots about vitamin B-12 and folate here )
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Biochemistry: Amino Group Metabolism, Heme Metabolism
What are the inputs and outputs from the amino acid pool?
--Inputs: diet, stomach digestion, pepsinogen, pancreatic enzymes, intestinal processing, absorption, turnover of endogenous proteins
--Outputs: excretion, protein building in fed state, aa catabolism during a fast
( more )
--Inputs: diet, stomach digestion, pepsinogen, pancreatic enzymes, intestinal processing, absorption, turnover of endogenous proteins
--Outputs: excretion, protein building in fed state, aa catabolism during a fast
( more )
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Biochemistry: Reactive Oxygen Species and Detox Mechanisms
Free radical = a solitary electron in a shell on an atom, looking for a partner. Very reactive, and can steal partners from other atoms and injure cells.
( on free radicals, antioxidants and detoxing )
( on free radicals, antioxidants and detoxing )
Organ Systems II: Calcium, Phosphorus & Vitamin D
Calcium regulates nerve excitability and muscle contraction. Low calcium results in muscle twitches. Calcium competes with sodium for voltage gated channels. Calcium also plays a part in neurotransmitter release, blood clotting, bone composition (hydroxyapatite).
( more )
( more )
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