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US Deaths from opioid overdose tripled between 1999 and 2006 according to CDC Data. The drug leading the charge for the grave was methadone.
http://www.medscape.com/viewarticle/709744?src=mpnews&spon=12&uac=89474MT
I talked to a junkie on bus#9 the other day who had been through hell but not died. He had a good idea what his protocol would be for getting people unhooked from methadone. It involved taking pts through a series of other high powered drugs, each to be given for a time period just short of the dependence/addiction-inducing timeframe. He was sure his method would work.

Re: there is a study in there...

Date: 2009-10-03 11:52 pm (UTC)
From: [identity profile] beauregard45.livejournal.com
chewing. If a pill is in the sustained release form, chewing it negates the slow release of the medication and it is as if a person took multiple doses that then release at the same time. Result? Instant rush. Stonerville. Same as crushing and then snorting Oxycontin (a sustained release form of oxycodone).

But this does not address half life of a drug. Methadone is maybe not packaged in a sustained release form, but it has a very long half life. I do believe this is the trait that the clinicians are hoping will allow the addict to then transition down in dosage, and eventually off of an opioid.

So, for my understanding, chewing of a pain med is never a good idea, and the same goes for things like ambien, some stomach meds, and any drug meant to be dispersed in the body over time.

Lots of demented seniors in nursing homes will chew instead of swallow their pills. They either then spit them out, a real mess, or swallow them in a masticated form. Usually not a good idea. But they just don't comprehend it any other way.

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