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on GARDASIL from http://www.gardasil.com/:

(This text swiped directly from the gardasil website and definitely NOT what I would consider to be TRUE: this is MARKETING. My comments in parenthesis throughout.)

GARDASIL is the only vaccine that may help guard against diseases that are caused by human papillomavirus (HPV) Types 6, 11, 16, and 18:
• Cervical cancer
• Cervical abnormalities that can sometimes lead to cervical cancer
• Genital warts

(Notice the use of the word MAY! They're not even going so far out on the limb as to say that their vaccine actually DOES guard, it only MAY guard. Weak.)

HPV Types 16 and 18 cause 70% of cervical cancer cases, and HPV Types 6 and 11 cause 90% of genital warts cases.

(They sure throw about this "causality" as if they were sure of it. How do you prove causality? It's not easy. More likely they have seen a correlation.)

IMPORTANT INFORMATION ABOUT GARDASIL
GARDASIL may not fully protect everyone and does not prevent all types of cervical cancer, so it is important to continue regular cervical cancer screenings.
(may not)
Anyone who is allergic to the ingredients of GARDASIL should not receive the vaccine.
(what are the ingredients so that I can assess my potential allergic issues?)
GARDASIL is not for women who are pregnant.
GARDASIL will not treat cervical cancer and genital warts and will not protect against diseases caused by other HPV types.
GARDASIL is given as 3 injections over 6 months and can cause pain, swelling, itching, and redness at the injection site, fever, nausea, and dizziness.
Only a doctor or healthcare professional can decide if GARDASIL is right for you or your daughter. Ask about GARDASIL today.
(you can't decide for yourself, according to them ONLY A DOCTOR can decide for you)

GARDASIL is for girls and women ages 9 to 26. GARDASIL works when given before you have any contact with HPV Types 6, 11, 16, and 18.

(Age range: 9-26. What about us older ladies? Don't you care about US getting cervical cancer? Or do you think we don't have sex anymore? That's what you might think if you get your reality checks from TV and movies.)

If you've already been infected with HPV, you may still benefit from GARDASIL because it is unlikely that you have been infected with all 4 types of the virus covered by the vaccine. Your doctor or healthcare professional can help you understand more.

(Wouldn't want to limit the market by ruling out folks who already have one kind of virus!)

Here's what the people have to say:
http://en.wikipedia.org/wiki/Gardasil

From wikipedia:

Safety and efficacy of the vaccine
According to the Centers for Disease Control, the vaccine was tested in over 11,000 females (ages 9 to 26). These studies have shown no serious side effects. The most common side effect is soreness at the injection site. CDC, working with the FDA, will continue to monitor the safety of the vaccine after it is in general use. ***The vaccine does not contain mercury, thimerosal or live virus.[4]

(INGREDIENTS: NO MERCURY, THIMEROSAL-the mercury-containing ingredient, or LIVE VIRUS. We can presume it contains dead virus parts, because that's what a vaccine is. What are the other ingredients???)

The National Cancer Institute says, "FDA-approved Gardasil prevented 100 percent of the precancerous cervical cell changes caused by the types of HPV targeted by the vaccine for up to 4 years after vaccination."

Darren Brown, Indiana University, reported at the 2007 Interscience Conference on Antimicrobial Agents and Chemotherapy that Gardasil had 38% efficacy against 10 other HPV types responsible for >20% of cervical cancer cases.

APPROVED BY THE FDA: on June 8, 2006.

CDC: According to the American Centers for Disease Control, getting as many girls vaccinated as early and as quickly as possible will reduce the cases of cervical cancer among middle-aged women in 30 to 40 years and reduce the transmission of this highly communicable disease. Unfortunately, there are hurdles to getting this done. These include the limited understanding by many people that HPV causes cervical cancer, the difficulty of getting pre-teens and teens into the doctor’s office to get a shot, and the high cost of the vaccine

COST OF VACCINE AND MANDATORY SHOTS AS COST CONTROL MECHANISM: ($120/dose, $360 total for the three required doses, plus the cost of doctor visits). One way to bring down the cost of the vaccine and to educate the public on the benefits of vaccination is to make it mandatory for girls entering school. This approach has been taken with vaccines for mumps, measles, rubella, and hepatitis B (which is also sexually transmitted) so many state legislators have penned bills that do this. Almost all pieces of legislation currently pending in the states that would make the vaccine mandatory for school entrance have an "opt-out" policy.

THE OTHER VACCINE IS NAMED: Cervarix

Lots of interesting articles from an anti-vaccine org:
http://www.nvic.org/Diseases/HPV/HPVHOME.htm

More info for Clinical Correlates

Date: 2008-01-09 03:13 am (UTC)
From: (Anonymous)
Teresa,
There are several points in this debate that I think are worth chatting about. In addition to the fundamental debate over the safety of vaccines as a whole, this case highlights the juncture between politics, community health, and big pharm/money-making ventures. Billions of dollars have been spent by Merck trying to push through legislation to mandate a vaccine that has been approved by the FDA for less than 5 years - you bet I think they are trying to push through this legislation before the other company gets there version of the vaccine out on the market and takes profits away from Merck. It would be so unfortunate for the fellows over at Big Pharm if the same amount of resources and energy were poured into an educational campaign regarding nutritional therapy for cervical dysplasia. Anyways, I attached some links below to articles that I found interesting. I will print out pertinent ones for class.

**There is much debate around the efficacy of the vaccine in the long-term. While articles like this one are out there, we have to pay attention to the short-term nature of our knowledge around the efficacy particularly when one notes that the average age women are diagnosed with HPV is not until after the approved time frame for administration of the vaccine.

Long-term efficacy of human papillomavirus vaccination

Kevin A. AultCorresponding Author Contact Information, a, E-mail The Corresponding Author
aDivision of Gynecologic Oncology, Department of Gynecology and Obstetrics, Emory University School of Medicine, 69 Jesse Hill Drive, Atlanta, GA 30064, USA
Received 24 July 2007. Available online 12 October 2007.

**Info on 2007 State Legislation concerning mandating the HPV vaccine:
http://www.ncsl.org/programs/health/HPVvaccine.htm

**More insight into the information that is being dispelled out there. This is what the CDC has to say to healthcare providers:

http://www.cdc.gov/std/hpv/hpv-vacc-hcp-3-pages.pdf

-sara

Re: More info for Clinical Correlates

Date: 2008-01-09 03:43 am (UTC)
From: [identity profile] liveonearth.livejournal.com
Awesome followup! Let's keep reading on it. Let me know if you get some ideas as to how to organize our presentation! -T

Re: More info for Clinical Correlates

Date: 2008-01-14 04:02 am (UTC)
From: (Anonymous)
Teresa,
Perhaps we could first present the nitty gritty on the vaccine. Ie: which strains is it meant to treat, what are the claims regarding its efficacy, etc. We could then present the counter-arguments to that information (safety, lack of info on long-term efficacy), followed by an overview of the political goodness that surrounds this one. I think this topic will easily open itself up to quite a bit of discussion and I would love to spark the conversation in folks :) What do you think?

Re: More info for Clinical Correlates

Date: 2008-01-14 04:38 am (UTC)
From: [identity profile] liveonearth.livejournal.com
Sounds like a good general game plan. See you tomorrow!

Date: 2008-01-10 04:03 am (UTC)
From: [identity profile] kellamaste.livejournal.com
The ingredients include “...inactive proteins from HPV Types 6, 11, 16, 18, amorphous aluminum, hydroxyphosphate sulfate, sodium chloride, L-histine, polysorbate 80, sodium borate, and water...”

From: http://depts.washington.edu/hhpccweb/article-detail.php?ArticleID=340&ClinicID=17

Sodium borate (Borax) has been illegal as a food additive in the US for a while. Interesting non?

Date: 2008-01-10 04:58 am (UTC)
From: [identity profile] liveonearth.livejournal.com
Interesante! Thanks for sending.

From Wikipedia:
Boric acid, sodium borate, and sodium perborate are estimated to have a lethal dose (LD50) from 0.1 to 0.5 g/kg in humans. These substances are toxic to all cells, and have a slow excretion rate through the kidneys. Kidney toxicity is the greatest, with liver fatty degeneration, cerebral edema, and gastroenteritis. A reassessment of boric acid/borax by the United States Environmental Protection Agency Office of Pesticide Programs found potential developmental toxicity (especially effects on the testes). Boric acid solutions used as an eye wash or on abraded skin are known to be especially toxic to infants, especially after repeated use because of its slow elimination rate.

Date: 2008-01-10 04:59 am (UTC)
From: [identity profile] kellamaste.livejournal.com
Scary stuff.

adverse effects

Date: 2008-01-10 05:00 am (UTC)
From: [identity profile] liveonearth.livejournal.com
http://articles.mercola.com/sites/articles/archive/2007/07/24/gardasil-reactions-and-deaths-on-the-rise.aspx

states on Merck's list

Date: 2008-01-10 05:03 am (UTC)
From: [identity profile] liveonearth.livejournal.com
Vaccination of girls is already mandatory in Texas. Here's an article that lists the states where Merck is hard at work getting us to buy their vaccine without questions:
http://www.kaisernetwork.org/daily_reports/rep_index.cfm?DR_ID=42648

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