May. 13th, 2008

liveonearth: (Default)
1. The following article was published this May in the Journal of
Clinical Immunology:

"Recurrence of autoreactive antigen-specific CD4+ T cells in
autoimmune diabetes after pancreas transplantation
CD4+ T cells specific for the diabetes-associated autoantigen GAD65
were analyzed using peripheral blood samples after pancreas
transplantation in subjects with T1D with clinical evidence of
recurrent autoimmune diabetes. Comparisons of TCR clonotypes by cDNA
sequencing revealed that identical T cells were present in the
circulation, separated by long time intervals, consistent with a
persistent memory response associated with recurrent autoimmunity."

Which cell and receptors are responsible for identifying the new
pancreas as foreign with the CD4 cells? What is alloreactivity?
Describe the cascade of events leading to the recurrence of
autoimmunity post-transplantation.
first stab at answers )
liveonearth: (Default)
Name___me_________________________
1. Little Efram is highly susceptible to skin infections. You suspect that he has a problem with his defensins. Tell him about defensins-- what they do, how they work, etc. (5 pts) What could you do (if you had a laboratory) to test if defensins are truly missing on the Efram's skin? (2 pts)
hazy answers, refinement needed )

Profile

liveonearth: (Default)
liveonearth

May 2025

S M T W T F S
    123
45678910
11121314151617
1819202122 2324
25262728293031

Most Popular Tags

Style Credit

Expand Cut Tags

No cut tags
Page generated May. 29th, 2025 09:16 am
Powered by Dreamwidth Studios