More Fake Sugar: Sucralose (brand name Splenda)

Sounds like, from this and other articles, that sucralose is not as toxic as aspartame, however because the product is brand new and relatively untested (certainly no long term testing on record), there's no guarantee that it won't hurt you. The best things to eat are the things that we evolved eating. "Natural" foods that have been chemically altered are not to be considered "safe" until time-tested.

http://www.mercola.com/2000/dec/3/sucralose_dangers.htm