Digestion of Lipids

[liveonearth]

What enzyme in the mouth begins lipid digestion?
lingual lipase

What can lingual lipase digest?
TGs-->monoglycerides, and FFA

What enzyme in infants turns milk into paracasein?
rennin aka chymosin

What cells make rennin in infants?
gastric chief cells

What enzyme then digests the paracasein?
pepsin

What adult gastric enzyme hydrolyzes TGs, short and medium chain fatty acids?
gastric lipase

Where do the hydrolyzed fats go from the stomach?
into the portal circulation

What causes micelle formation in the intestine?
bile
emulsifies

What happens to the micelles?
they are absorbed into intestinal cells where they are
re-esterified and packaged into chylomicrons
then exocytosed into lymph system

What hydrolyzes cholysteryl esters to free cholesterol???
cholesterol esterase

What enzymes attacks phospholipids to produce FFA, glycerol, choline (bases) and phosphoric acid?
phospholipase
remember phospholipase A is the one that gets fatty acids out of membranes

Where do the non-lingual lipases come from?
pancreas

Comments

[newedition.livejournal.com]

Yep, I have an M.S. in cell / molecular biology, so I especially like looking at the biochemical pathways! Too many nutrition books focus on the macro level and never explain the principles biochemically. Many years down the road I'd like to write a book about nutritional biochemistry. There are some available, but I think it would be fun to "trace a meal" from mouth to cell and then back to the whole body system level.

[liveonearth.livejournal.com]

Sounds like the basis for an amazing book. What meal will you trace???

[newedition.livejournal.com]

No idea yet... probably something wild and crazy that has a fantastic balance of protein, carbohydrates, and fats... maybe quinoa with coconut and some funky vegetables. I'll save this post as a bookmark so I remember it in a few years :-)
(And BTW, I am one of those people who really does follow through!)

[liveonearth.livejournal.com]

Mmmmmm. Quinoa with a yellow curry--onions, peas, carrots, you name it. Must have some animal product just so you can teach about heme absorption and vitamin B12 and all. Or maybe have a chapter on what's missing from that meal. I can't wait!!