ext_211332 ([identity profile] liveonearth.livejournal.com) wrote in [personal profile] liveonearth 2009-08-01 02:13 pm (UTC)

smoking kicks adrenals into high gear

Awesome links! Thanks. I am hereby more educated than I was.

Smoking acutely elevates not just cortisol from the adrenal zona fasciculata, but also catecholamines (dopa-->norepi-->epi) from the adrenal medulla and DHEA production from the zona reticularis. I had no idea that cigs were responsible for such adrenal overstimulation. It kind of makes sense esp when I think of smokers I know who crave that very first morning cigarette the most. Because they need the kick to get their adrenals working! Cool.

There is also a relaxing effect of cigs, that has something to do with the binding of nicotinic receptors. Know anything about that?

I have to focus on other matters for a few days, I will be interested to hear the results of your cortisol test! The fact that you are sleeping better is pretty convincing. I bet your levels have already normalized.

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