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Treat Vascular Risk Factors to Slow Alzheimer's Progression
pearl: statins and fibrates both affect amyloid protein and reduce cognitive decline in hyperlipidemic patients until the decline less that patients without hyperlipidemia in the first place
pearl: treating atherosclerosis slows progression of dementia
notes from medscape
( Treating Vascular Risk Factors Slows Cognitive Decline in Alzheimers Disease )
pearl: treating atherosclerosis slows progression of dementia
notes from medscape
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Placebos getting More Effective
http://www.wired.com/medtech/drugs/magazine/17-09/ff_placebo_effect?currentPage=all
AWESOME article. Nutshell: research has show that the biochemistry of the placebo response is due to anticipation-activated opioids and dopamine. Effects of opioids include pain relief, heart rate and breathing modulation. Effects of dopamine include improved motor function in Parkinson's. Both contribute to elevated mood, sharpened cognitive ability, decreased digestive disorders and insomnia, and lower levels of insulin and cortisol. But the whole article is well worth reading.
( Here's the text. I would take notes but I admire this guy's prose too much to chop it up. This article matters. )
AWESOME article. Nutshell: research has show that the biochemistry of the placebo response is due to anticipation-activated opioids and dopamine. Effects of opioids include pain relief, heart rate and breathing modulation. Effects of dopamine include improved motor function in Parkinson's. Both contribute to elevated mood, sharpened cognitive ability, decreased digestive disorders and insomnia, and lower levels of insulin and cortisol. But the whole article is well worth reading.
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Veterans with PTSD have 2x More Dementia
The incidence of dementia is increasing even faster than the incidence of cancer!!
This won't help one bit.
Headline:
PTSD Linked to 2-fold Increased Risk for Dementia in Veterans
Caroline Cassels
( from Medscape, on the first study re this question )
This won't help one bit.
Headline:
PTSD Linked to 2-fold Increased Risk for Dementia in Veterans
Caroline Cassels
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Pathology of the CNS: part 4, Dementia
What sorts of dementia may be reversible?
( part 4 Miller notes on dementias: Parkinson's dz, demyelinating dz, multi-infarct, Alzheimer's )
Books: on Risk Taking and Survival

Just started reading Deep Survival, and already it has grabbed me. The author Laurence Gonzales knows about the brain, about memory and emotion and the ways that we humans operate. I don't entirely agree with his presentation of brain function--it is a little simplistic--but overall it is a useful framework. I'm on page 67 at the moment, and there are a couple of quotes I'd like to record here:
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Eat Celery for Brain Health
http://www.timesonline.co.uk/tol/life_and_style/food_and_drink/real_food/article3953710.ece
May 18, 2008
‘Superfood’ celery combats brain diseases
Jonathan Leake, Science Editor
( article text )
May 18, 2008
‘Superfood’ celery combats brain diseases
Jonathan Leake, Science Editor